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Healthy Heart Reports

Evidence That Chlamydia Causes Heart Attacks

A recent issue of the American College of Cardiology lists 15 papers showing the overwhelming evidence that heart attacks are caused by infections as well as by certain dietary fats, obesity, smoking and lack of certain vitamins. Recent reports from Germany and Italy show that chlamydia is found in arterial plaques and at much higher than normal levels in blood of people who suffer heart attacks (16,17,18). Men with circulating chlamydia DNA are at high risk for heart attacks (1). Herpes virus causes arteriosclerosis in chickens (3). Cytomegalovirus causes arteriosclerotic heart disease in men who have had heart transplants (4). Chlamydia causes accumulation of foam cells and oxidation of cholesterol, two key changes that prevented the formation of arteriosclerotic plaques (5). The surface protein of chlamydia shares surface protein with blood vessels, so immune antibodies that attack. chlamydia may indeed damage blood vessels (6). Chlamydia is very common, causing 10% of pneumonias worldwide (7). Chlamydia damages cultured arteries removed from animals and placed in a test tube (9). Chlamydia causes the same damage in rats and chickens as it does in humans (10). People with dental infections are at increased risk for suffering heart attacks (11). Chlamydia pneumoniae, cytomegalovirus, herpes simplex virus, and periodontal disease caused by Porphyromonas gingivalis and Streptococcus sanguis are associated wit increased risk for heart attacks (12). Antibiotics that kill chlamydia prevent heart attacks (13). The recently completed WIZARD study shows that Zithromax prevents second heart attacks (14, 15).

1)YK Wong, KD Dawkins, ME Ward.Circulating Chlamydia pneumoniae DNA as a predictor of coronary artery disease. Journal of the American College of Cardiology, 1999, Vol 34, Iss 5, pp 1435-1439.

2) VV Valtonen.Role of infections in atherosclerosis.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S431-S433.

3) CG Fabricant, JFabricantle.Atherosclerosis induced by infection with Marek's disease herpesvirus in chickens.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S465-S468.

4) JD Hosenpud.Coronary artery disease after heart transplantation and its relation to cytomegalovirus.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S469-S472.

5) GI Byrne, MV Kalayoglu.Chlamydia pneumoniae and atherosclerosis: Links to the disease process.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S488-S490.

6) G Christiansen, T Boesen, K Hjerno, L Daugaard, P Mygind, AS Madsen, K Knudsen, E Falk, S Birkelund.Molecular biology of Chlamydia pneumoniae surface proteins and their role in immunopathogenicity.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S491-S495.

7) P Saikku.Epidemiology of Chlamydia pneumoniae in atherosclerosis.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S500-S503.

8) M Leinonen, P Saikku.Interaction of Chlamydia pneumoniae infection with other risk factors of atherosclerosis.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S504-S506.

9) TC Quinn, CA Gaydos.In vitro infection and pathogenesis of Chlamydia pneumoniae in endovascular cells.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S507-S511.

10) IW Fong.Value of animal models for Chlamydia pneumoniae-related atherosclerosis.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S512-S513. 11) JD Beck, J Pankow, HA Tyroler, S Offenbacher.Dental infections and atherosclerosis.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S528-S533.

12) B Chiu.Multiple infections in carotid atherosclerotic plaques. American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S534-S536.

13) EP Gurfinkel, G Bozovich.Trials of anti-chlamydial therapy - Emerging role of antibiotics in atherosclerosis.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S537-S538.

14) M Dunne.WIZARD and the design of trials for secondary prevention of atherosclerosis with antibiotics.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S542-S544.

15) JT Grayston, LA Jackson, WJ Kennedy, RA Kronmal.Secondary prevention trials for coronary artery disease with antibiotic treatment for Chlamydia pneumoniae: Design issues.American Heart Journal, 1999, Vol 138, Iss 5, Part 2, Suppl. S, pp S545-S549.

16) G Bauriedel, R Andrie, JA Likungu, A Welz, P Braun, U Welsch, B Luderitz Persistence of Chlamydia pneumoniae in coronary plaque tissue: a contribution to the infection and immune hypothesis concerning unstable angina. Deutsche Medizinische Wochenschrift, 1999, Vol 124, Iss 47, pp 1408-1413.

17) F Blasi, J Boman, G Esposito, G Melissano, R Chiesa, R Cosentini, P Tarsia, Y Tshomba, M Betti, M Alessi, N Morelli, L Allegra. Chlamydia pneumoniae DNA detection in peripheral blood mononuclear cells is predictive of vascular infection. Journal of Infectious Diseases, 1999, Vol 180, Iss 6, pp 2074-2076.

18) J Kahler, R Koster, JH Braser, P Schafer, W Terres, CW Hamm, T Meinertz. Role of Chlamydia pneumoniae in the pathogenesis of coronary artery disease. Zeitschrift Fur Kardiologie, 1999, Vol 88, Iss 11, pp 885-895.

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Copyright 2000 www.DrMirkin.com
Dr. Mirkin's opinions and the references cited are for information only, and are not intended to diagnose or prescribe. For your specific diagnosis and treatment, consult your doctor or health care provider.

For more recipes, refer to the The Healthy Heart Miracle book.